Does caffeine increase the effectiveness of oxandrolone?

What is Oxandrolone (Anavar Steroid)?

Oxandrolone or Anavar Steroid (brand name) was originally described by two scientists namely: Christopher J. Jung and Raphael Pappo who worked for Searle Laboratories (now owned by Pfizer) in 1962.

Oxandrolone is an androgenic-anabolic steroid that has a strong anabolic effect, but with weak androgenic properties. It was in 1964 that this steroid would be made available in the US market as an FDA approved pharmaceutical drug.

Originally recommended by qualified physicians in the treatment of wasting syndromes like cancer and to build strength and physique in patients after surgery. However, the importance of the Anavar steroid for improving sports performance would soon be recognized by sports scientists and athletes.

This led to the use of theOxandrolone by athletes in various sports, including weightlifting, powerlifting and bodybuilding. In time, Anavar would be classified and listed under the United States Anabolic Steroids Control Act of 1990 as one of many Schedule III controlled substances along with other similar androgen-anabolic steroids (AAS).

Besides being used to bring about weight gains in patients recovering from surgery, Oxandrolone is also used medically in the treatment of osteoporosis, Turner syndrome and burn victims.

As a popular anabolic among athletes, the Anavar steroid helps improve bone density and build lean muscle mass. A well-tolerated drug, Anavar is used by male bodybuilders and female looking for fantastic anabolic gains without harsh androgenic effects.

Anavar is available as an orally administered drug with low hepatotoxicity. This is great news for shy athletes and those who express real concerns about the drug's adverse effects on their vital organs like their kidneys and liver.

Anavar has very little to no negative effect on the liver, even when high doses are consumed. However, users should be careful when administering Oxandrolone to avoid issues of misuse, abuse, and addiction.

Although Oxandrolone is not as hepatotoxic as other AAS, there are still notable side effects ofAnavar, especially in female users, of which you should be aware. Some of these side effects include:

1. An increased propensity for acne
2. thinning hair on the scalp of the head
3. An increased likelihood of developing male pattern baldness
4. Hirsutism
5. A deeper male voice
6. Increased growth of facial and body hair
7. Enlargement of the clitoris
8. Abnormal and disrupted menstrual cycles

These are the most common Anavar side effects affecting female users. Although Anavar does not cause gynecomastia in male users, it may adversely affect their fertility by causing a drop in natural testosterone production due to constrained gonadotropic activity and testicular atrophy. .

 

What is the relationship between oxandrolone and caffeine?

A question potential Oxandrolone users often ask is “how long does Anavar stay in your system?”. Well, the elimination half-life of the Anavar steroid is between 9.4 and around 10.4 hours in young adults and middle aged users.

However, in elderly users, the elimination half-life of Oxandrolone is approximately 13.3 hours, with approximately 3% of orally administered unchanged Anavar being eliminated via your stool and nearly 28% eliminated in your urine.

Another question that people often ask themselves when it comes to Anavar is "what is the relationship between Oxandrolone and caffeine?" Even though the steroid Anavar has an oral bioavailability of 97%, it is believed that this percentage may be further increased when Anavar is taken with caffeine (Coffee).

In a study in Portugal, researchers found that Oxandrolone users experienced more anabolic gains when the steroid was used with caffeine than when taken alone. In their study, a test subject had to drink at least three cups of espresso containing 64 mg of caffeine in one of the cups of espresso consumed.

In addition to drinking caffeine, this test subject was also given Oxandrolone (0.4 mg) and carefully monitored for a period of 40 hours. The researchers wanted to know the volume of Epioxandrolone, an inactive metabolite of Oxandrolone, Oxandrolone and caffeine that would be expelled in the subject's urine.

The idea was to see if consuming caffeine had a significant effect on increasing the oral bioavailability of the steroid Anavar in the test subject's body. The researchers would later repeat the study, but this time they would increase the caffeine dose from 64 mg to 300 mg and the subject's monitoring period from 40 to 70 hours.

Although this research was conducted on a single subject, the results (as you will see a little later) still suggested that caffeine consumption had a positive effect on the rate of absorption of Oxandrolone into the body.

Bodybuilders using the steroid Anavar as part of their workout routine can consume a cup of caffeinated coffee to enhance the effects of Oxandrolone on their body before engaging in their workout routine.

Result of a study on oxandrolone and caffeine

From the study highlighted above, it was found that the maximum amount of Oxandrolone urinated by the subject prior to caffeine use was only 10 ng/min. However, after caffeine consumption, the subject had urinated 150 ng/min of Oxandrolone.

In the case of the inactive metabolite Oxandrolone – Epioxandrolone, the amount urinated before caffeine consumption was 0.9 ng/min, but after caffeine consumption the amount increased to 19 ng/min. It should also be noted that the maximum amount of Oxandrolone and Epioxandrolone that was excreted by the subject and recorded after caffeine consumption occurred within 4-6 hours of the study.

The result of this study was that the volume of Epioxandrolone and Oxandrolone found in the subject's urine was significantly increased by more than (15 and 20 times respectively) proving that the effects of caffeine on the oral bioavailability of the Oxandrolone were clearly incremental in nature.

 

Anavar steroid product description

Oxandrolone is available in a number of brands like Anavar and Oxandrin. This synthetic androstane drug is 17B-hydroxy-17a-methyl-2-oxa-5a-androstan-3-one, a 17α-alkylated derivative of DHT composed of inactive ingredients, such as: lactose, hydroxypropyl methyl-cellulose, stearate of magnesium and cornstarch,

Whenever you buy Anavar Oxandrolone, you can expect to get the drug in either the 2.5mg per pill or 10mg per pill package. As for drug interactions, Anavar steroid use is known to increase a user's sensitivity to oral anticoagulant intake and these medications may need to be discontinued if Anavar administration persists.

The Oxandrolone product is also known to limit the metabolic rate of orally administered hypoglycemic agents. You can buy Anavar Oxandrolone online from a number of reputable pharmaceutical companies usually located in Europe and Asia.

 

Conclusion

Oxandrolone is an ASA that tops the list of bodybuilders who want the anabolic benefits of increased muscle mass, stronger muscle tissue, improved bone density and increased strength without having to inject themselves to achieve it.

Oral administration of Anavar steroids is mild on the liver and primarily metabolized by the kidneys. Male users need not worry about gynecomastia, but female users should beware of masculinization.

Oxandrolone has a relatively high oral availability, but this can be improved with caffeine consumption, as suggested by the results of a study conducted by researchers in Portugal and highlighted in this article.

Although this AAS is relatively safe to use, it is advisable to consult your doctor before using Oxandrolone. This is important in order to avoid complications due to undiagnosed health conditions that you may be suffering from.